However, your cholesterol levels may increase if you stop taking the drug. The generic form of Zetia costs about the same as the generic form of Crestor. As with most drugs, some people can have an allergic reaction after taking Zetia. Zetia hasnt been studied in certain types of dyslipidemia, including Frederickson types I, III, IV, and V. Zetia is taken orally with or without food. Read More. weakness and fatigue (tiredness) headaches. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. Based on animal studies, Zetia may cause harm to the fetus when taken by a pregnant woman. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. Currently, no medications have been approved by the FDA to treat POTS. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. Have your doctor measure your heart rate sitting and standing. People with HoFH have high levels of LDL (bad) cholesterol. Ask your doctor what other medications are better options for you. Statin drugs arent safe to use during pregnancy. This lack of blood to the brain and other organs can cause a variety of symptoms, including: Fainting. Clinical studies involved adults and children ages 10 years and older. Theyll likely suggest changes to your treatment plan. Recently, POTS has been diagnosed in some people who have had COVID-19. Statins, another medication for high cholesterol, are known to cause muscle-related side effects. Zetia is sometimes used with medications in the statin drug class. This article provides several useful tips on medication disposal. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. But if they become more severe or dont go away, talk with your doctor or pharmacist. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). Zetia can also be used with statin drugs in adults. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Zetia may also be used off-label for other conditions. But in studies, some people had to stop taking the drug due to feeling dizzy. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Zetia. Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. Total cholesterol is the overall amount of cholesterol found in your blood. For some drugs, doing so may lead to unwanted side effects or overdose. pain in your arms or legs. Both Zetia and Lipitor come as tablets that are swallowed. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. These problems can include muscle pain and muscle weakness, and rarely, muscle breakdown. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. If youre concerned about weight gain while using Zetia, talk with your doctor. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. During your Zetia treatment, consider keeping notes on any side effects youre having. This can raise your levels of these drugs and increase your risk of side effects. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. Your child can take Zetia with or without food. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Side effects could occur in children who are breastfed by someone taking a statin drug. Most of Zetias side effects should go away within a few days or weeks. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). But over time, heavy alcohol use can damage your liver. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. These tests will look at your cholesterol levels and also your liver enzyme levels. Zetia isnt a statin drug. Taking Zetia with a statin may cause this side effect. Doing this can raise your risk of side effects. If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. Would a lower dose of Zetia help to reduce my risk of side effects? Crestor contains the active drug rosuvastatin. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. Also tell them about any vitamins, herbs, and supplements you use. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. MNT is the registered trade mark of Healthline Media. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Less commonly, taking Zetia may lead to serious side effects. Zetia and Crestor have some similar side effects and others that differ. Zetia contains the active drug ezetimibe. In clinical studies, Zetia has been found to be effective for treating mixed high cholesterol when used with fenofibrate. Lipitor and Zetia belong to different drug classes. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. * For more information about this side effect, see " Zetia: Side effects explained " below. How long a medication remains good can depend on many factors, including how and where you store the medication. Both drugs are typically taken once each day. Zetia and Lipitor have some similar side effects and others that vary. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. (For information on side effects, see the Zetia side effects section above.). Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. zetia. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. It can cause mild side effects and, less commonly, serious side effects. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. We've provided a list of the best at-home tests for. What Are the Injectable Alternatives to Statins? They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. joint pain *. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. You can take Zetia at any time during the day, but try to take your dose around the same time each day. This can increase your risk of side effects from either medication. Zetia is primarily cleared from the body through fecal excretion. Read more about how inherited high cholesterol affects life expectancy and what makes it different from regular hypercholesterolemia. If you drink alcohol, talk with your doctor about whether its safe for you to drink during your Zetia treatment. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. Your doctor will determine the best dosage to fit your needs. What causes POTS? It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The side effects of Zetia in children are similar to the side effects in adults. As with all medications, the cost of Zetia can vary. If youre concerned about joint pain while using Zetia, talk with your doctor. Medications in the fibrate drug class are used to treat high cholesterol. Zetia can interact with several other medications. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. Learn about side effects, dosage, uses, interactions, and more. For most people, CoQ10 isnt a harmful or dangerous supplement. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. However, if the side effects last longer than . The heart beats faster to pump it up to the brain, but with little success. Porphyria patients are often overly sensitive to sunlight. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. The insurance company will review the prior authorization request and decide if the drug will be covered. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. Plant sterols are similar to cholesterol. This is because large meals can cause blood to pool excessively in the abdomen. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. Zetia can cause muscle-related side effects. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. These lists contain examples of serious side effects that can occur with Lipitor or with both drugs (when taken individually). These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). For instance, some interactions can interfere with how well a drug works. Learn about the side effects it can cause and how to manage them. The generic is considered to be as safe and effective as the original drug. (A class of medications is a group of drugs that work in a similar way.) They can tell you about other medications that may work well for you. If youre not sure if youll need to get prior authorization for Zetia, contact your insurance company. This in turn increases clearance of cholesterol from the blood. Get medical help right away, if you have any of the symptoms listed above. It can cause mild side effects and, less commonly, serious side effects. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. Heres some detail on certain side effects this drug may or may not cause. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. Drugs in this class prevent your small intestine from absorbing cholesterol. Your doctor may prescribe Zetia with a statin drug. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. shortness of breath or troubled breathing. The actual price youll pay for any of these drugs depends on your treatment plan, your insurance plan, your location, and the pharmacy you use. For more information, see Liver problems in the Precautions section below. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. Dr. John Szawaluk answered. Talk with your doctor about your health history before you take Zetia. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. Others may experience GI issues in conjunction with other symptoms, such as fainting. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. And talk with your doctor if you have any questions about eating certain foods with Zetia. Symptoms: This section is currently in development. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Zetia may cause joint pain. Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. High cholesterol can raise your risk of heart disease. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. Zetia comes as a tablet that you swallow. Crestor is part of the statin drug class. Increased liver enzymes can be a sign of liver damage. The following information is provided for clinicians and other healthcare professionals. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Specifically, Zetia is used along with a low-cholesterol diet to treat: Zetia is approved to treat these conditions in certain situations. It's Aimee Esther here! But its not clear whether this side effect occurred in studies. In studies, some people had to stop taking Zetia because of this side effect. It only comes in a strength of 10 milligrams (mg). Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. These symptoms can be signs of an infection. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. 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